In subjects with IHD comorbid with AO, blood concentrations were lower for Flt3 ligand (1.5-fold), GM-CSF (2.3-fold), GROα (2.2-fold), and MCP-1 (1.9-fold), whereas IL-2 concentration in the blood was 3.0-fold higher relative to subjects with AO without IHD. This evidence concerns the gene CXCL1 and myocardial ischemia.