Resveratrol, as a polyphenol with powerful antioxidant properties inhibiting lipid accumulation, improving insulin sensitivity, and reducing triglyceride levels in serum, appears to be an effective, natural, and safe complementary treatment option in NAFLD therapy, particularly arising as a result of obesity and/or insulin resistance [2,36,37,38]. The gene discussed is INS; the disease is metabolic dysfunction-associated steatotic liver disease.