TNF and glaucoma: Liu et al. found [154] that the aqueous humor of patients with SO (especially those with secondary glaucoma) had increased concentration of inflammatory mediators Interleukin-17 (IL-17), Interleukin-6 (IL-6) and Tumor Necrosis Factor-α (TNF-α), confirming the hypothesis that inflammation is involved in the pathogenesis of this type of glaucoma.