EPHA2 and myocardial infarction: At 4 weeks post-MI, WT (n = 9) and EphA2-R-M (n = 10) fibrosis increased by 56% and 51% from control levels, respectively, with 1.66 ± 0.11% and 1.29 ± 0.15% of the tissues containing collagen fibers in the interstitium remote to the infarct in the same transverse plane (p < 0.001).