A similar result was also observed in a breast cancer study when CsH and Cyclosporin A (CsA) were used to inhibit FPR1 in MDA-MB-231 cell line [19], portraying a universal role that Anx-A1 might have in ameliorating cancer cell proliferation and PU’s effect on reducing the expression of Anx-A1 in HCT 116 could thus be translated to other types of malignancies. The gene discussed is ANXA1; the disease is cancer.