To study the pathological functions of CD83, we generated human CD83 stable overexpression (CD83-OV) and knockdown (CD83-KD) sublines of multiple ovarian cancer cells (e.g., SKOV3, OVCAR3, and Caov3), using infection of full-length CD83 lentivirus and triple CD83-specific lentiviral shRNA lentivirus, respectively. Here, CD83 is linked to ovarian carcinoma.