CD83 highly-associated genes, such as ITGAM, IL1B, CYBB, PIK3R5, BTK, and OSM, ectopically express in ovarian cancer cells or tissues, involving in ovarian cancer progression, hypoxia networks, and the development of chemoresistance [44,45,46,47,48,49]. The gene discussed is PIK3R5; the disease is ovarian cancer.