Other notable findings included higher observation in the IE group compard to the SCG group of SLIT2 (Slit Guidance Ligand 2 protein), an extracellular matrix protein and member of the SLIT family of proteins which has a role(s) in the blood brain barrier (BBB) integrity [37, 56] The mitochondrial protein MT-ND1 with epilepsy background was also found to be observed more in the IE group compared to the SCG group (40). The gene discussed is SLIT2; the disease is epilepsy.