CRP and hyperimmunoglobulinemia D with periodic fever: Clinical features of HIDS are similar to those of hereditary periodic fever syndromes, which include recurrent fever, lymphadenopathy, hepatomegaly, rash, arthritis, abdominal pain, and increased levels of biomarkers like serum amyloid A (SAA), serum IgD and C-Reactive Protein (CRP) [2].