Multivariate analysis revealed that only ALT level (OR = 1.084; 95% CI: 1.03–1.14; p = 0.004), obesity (OR = 2.64; 95% CI: 1.28–5.44; p = 0.008) and metabolic syndrome (OR 4.36; 95% CI 1.40–13.58; p = 0.011) were independent risk factors for hepatic steatosis. The gene discussed is GPT; the disease is obesity due to melanocortin 4 receptor deficiency.