CPAP: continuous positive airway pressure; BNP: brain natriuretic peptide; hs TropT: high sensitivity troponin; OSA: obstructive sleep apnea; NT-proBNP: N-Terminal pro-brain natriuretic peptide; RCT: randomized clinical trial; TTE: transthoracic echocardiography; OSAHS: obstructive sleep apnea-hypopnea syndrome; ANP: atrial natriuretic peptide; CMR: cardiac MRI. The gene discussed is NPPB; the disease is obstructive sleep apnea syndrome.