C9orf72 and amyotrophic lateral sclerosis: There was upregulation of terms related to the synaptic membrane and axoneme in non-C9orf72-associated ALS compared with C9orf72-associated ALS (e.g. “integral component of postsynaptic membrane”, 8/10 genes, normalized enrichment ratio 1.74, FDR-adjusted p = 0.044; “axoneme”, 6/10 proteins, ratio 1.71 FDR-adjusted p = 0.047; Fig. 7B and Additional file 1: Table S5).