PRRX1 and gastric cancer: Similarly, in gastric cancer, Guo et al15 found that overexpression of PRRX1 up‐regulated the intranuclear levels of β‐catenin and c‐Myc and promoted EMT, and XAV939, inhibitor of the Wnt/β‐catenin signing, abolish the role of PRRX1.