Besides, cyclin D1 and c‐Myc, direct target genes of β‐catenin, showed enhanced levels after the activity of Wnt/β‐catenin pathway38, 39 and played a critical role in the EMT of cancers including pancreatic cancer,40 NSCLC41 and oral squamous cell carcinoma.42 This evidence concerns the gene CCND1 and familial pancreatic carcinoma.