INS and Wilson disease: Furthermore, there was a tendency towards decreased insulin sensitivity at a few time points during ITT in C57BL/6J fed HFD compared to mice fed chow diet, but when calculating area over the curve (AOC) it only reached statistical significance between chow and HFD groups in C57BL/6JRj and between HFD and WD groups in C57BL/6J mice (Suppl.