Moreover, using FACS analysis (Table 1 and Fig. 5, A–G), CD4+, CD8+, and CD11b+ cells were significantly decreased in BALF and lungs cells, indicating that the over activation of the immune system caused by CFD was positively suppressed by the higher doses of KG3P and nepetin, decreasing the aggravation of inflammation. Here, CD4 is linked to fleck corneal dystrophy.