ATM and ANF were previously reported to block atypical PKC signaling by blocking the interaction between atypical PKCs and Par6, Ect2, or p6210,22 while Oncrasin-1 was found to only induce cell death in the presence of both mutant K-Ras and PKCι.23 However, MTT assay showed that the IC50 values calculated for ATM and Oncrasin were quite high compared to the published values for lung cancer. Here, PRKCI is linked to lung carcinoma.