Inhibition of MNK1 and MNK2 kinases could be the underlying mechanism for cercosporamide-mediated suppression of growth of human hepatocellular carcinoma and acute myeloid leukemia precursors (Altman et al., 2018; Konicek et al., 2011; Liu et al., 2016). This evidence concerns the gene MKNK2 and acute myeloid leukemia.