To further investigate the cellular mechanism underlying the gut microbiota-mediated autism-like behavior in EphB6-deficient mice, we recorded spontaneous excitatory postsynaptic currents (sEPSCs) and spontaneous inhibitory postsynaptic currents (sIPSCs) of mPFC pyramidal neurons in WT and KO mice treated with sterile PBS or the fecal microbiota from the WT mice (Fig. 8a). The gene discussed is EPHB6; the disease is autism.