The results indicated that patients’ ferritin, neutrophils, HB, platelets, alanine aminotransferase (ALT), AST, LDH, α-HBDH, DBIL, albumin, UREA, CREA, UA and Ca2+ were associated with the six-month prognosis in HLH patients (all P<0.05). This evidence concerns the gene GPT and hemophagocytic syndrome.