We found that six low-value procedures are significantly more likely to be provided in direct care: skin prick or IgE blood test for atopic dermatitis, testing for RSV in children with bronchiolitis, blood tests for simple febrile seizure, face or nose radiograph for children with head or face trauma, sinus imaging in children with acute sinusitis, and short-acting beta-antagonists for bronchiolitis. The gene discussed is IGHE; the disease is sinusitis.