IDH1 and glioblastoma: In this cohort, when analyzing the average age at diagnosis of different IDH1 phenotypes by using the whole cohort, no significant differences were observed (Supplementary Figure S1B and D); however, IDH-wt GBM was diagnosed at an older age than that of individuals diagnosed with IDH-mut GBM (Supplementary Figure S1A and C, 49.3 vs 43.2, respectively, p < 0.05).