Results indicate that 9 of 63 genes are statistically associated with GC patients’ survival such as FN1, ITGA11, ITGA5, ITGAV, LAMA2, LAMA4, LAMB1, THBS1 and TNN (P < .05) (Figure 5A), whose higher expression level may predict poor prognosis, whereas 9 of 63 genes have the same effects on the GC patients' survival, although not statistically significant, such as ITGA10, ITGA9, ITGB1, ITGB5, LAMA5, LAMC1, RELN, TNR and VTN (P < .1) (Figure 5B). The gene discussed is RELN; the disease is gastric cancer.