CD4 and major depressive disorder: All the variables that were significantly associated with either depression and suicidality were entered into a logistic regression, Gender (Wald 9.084, OR = 0.280, 95% CL 0.122–0.641), ACE (Wald 8.362, OR = 3.363, 95% CL 1.478–7.651) and Change in CD4 (Wald 6.987, OR = 0.240, 95% CL 0.083–0.692) count were the only variables that emerged in the final regression model to be independently associated with current major depressive episode.