Interestingly, 14 genes (WNT2, GADD45B, FZD2, CDKN1A, KRAS, LEF1, WNT7B, BAK1, BRCA2, CDK4, GRB2, HRAS, PIK3R3, and POLK) were associated with the breast cancer pathway (ID: hsa05224), even though is not in the top 30 KEGG pathways. The gene discussed is POLK; the disease is breast carcinoma.