We quantified adipose ACE2 expression levels in bulk RNA-Seq data from TwinsUK25,28,29 (765 female mono- and dizygotic twins), 426 males from the Metabolic Syndrome in Men (METSIM) study26, and 149 Finnish males and 131 Finnish females from the Finland-United States Investigation of NIDDM Genetics (FUSION) Tissue Biopsy Study27. Here, ACE2 is linked to type 2 diabetes mellitus.