Out of 64 samples collected from a cohort of 64 AML patients (see Figs. 2a, 3a, and 4a), we found 6 FLT3D835Y-positive cases, corresponding to a 9.4% rate, which is higher than the reported rate of all FLT3-TKD mutations in patients with AML of 3.8 to 7.7% [28–30]. The gene discussed is FLT3; the disease is acute myeloid leukemia.