In fact, the levels of the chemokines CXCL1 (growth related oncogene, GRO) and CCL2 (monocyte chemoattractant protein-1, MCP-1) varied in their expression along the demyelination process in taiep rats and contribute to the deficit of myelination by OPC, similar to multiple sclerosis (MS) patients [14]. This evidence concerns the gene CCL2 and multiple sclerosis.