GSTM1 and colon carcinoma: The change in Hb O2 saturation after T-State and R-State infusion determined in these simulations is also in agreement with the the O2 saturation of a low affinity (16 ± 10%) and high affinity (38 ± 8%) PEG-LEH as obtained with near infrared spectrocopy in a mouse colon carcinoma [18].