From the results of this computational analysis, we recommend implanting the same tumor cell line in two locations: (1) a tissue region with high Hb concentration (CHb,tis = 50 μM) such as murine rear flank and (2) a tissue region with low Hb concentration (CHb,tis < 45 μM) such as murine mammary fat pad. The gene discussed is GSTM1; the disease is neoplasm.