STAT4 and infection: Among the WT infection-specific upregulated genes in dTHP-1 cells (Fig. 3F), TLR8 (Toll-like receptor 8), CXCR4 (C-X-C chemokine receptor type 4), TLR9 (Toll-like receptor 9), STAT4 (signal transducer and activator of transcription 4), RASD1 (Ras-related dexamethasone-induced 1), and IKBKB (inhibitor of nuclear factor [NF]-ĸB kinase [IKK] subunit beta, also known as IKK-β) were upregulated more than 2-fold.