Specifically, we intravenously injected C57BL/6 mice with Lewis lung carcinoma cells as a model of orthotopic lung adenocarcinoma (Janker et al, 2018) and treated mice with anti–PD1 antibody (Li et al, 2017), in the presence or absence of Tα1. This evidence concerns the gene TAAR1 and lung adenocarcinoma.