For example, Charcot-Marie-Tooth (CMT) diseases have been linked to 870 mutations in over 80 genes (McCorquodale et al., 2016), such as PMP22, MPZ, GJB1 or MFN2 (Morena et al., 2019; Saporta et al., 2011). The gene discussed is MFN2; the disease is Charcot-Marie-Tooth disease.