Researches indicated that BIRC5 is overexpressed in various malignant tumors, and high expression level of BIRC5 predicted the poor clinical prognosis of these malignant tumor patients, such as malignant breast cancer,31 lung adenocarcinoma,32 neuroblastic malignant tumor,33 and malignant esophageal cancer.34 This evidence concerns the gene BIRC5 and lung adenocarcinoma.