In the turquoise gene module, 20 hub genes were identified positively correlated with CRC, including PAICS, ATR, AASDHPPT, DDX18, NUP107, TOMM6, GTPBP4, RAN, GPN3, SYNCRIP, CPSF3, PTRH2, SSRP1, BZW2, NEMP1, PTPMT1, CCT6A, HEATR1, TRIM27 and MRPL17 (Figure 8). This evidence concerns the gene SSRP1 and colorectal carcinoma.