In the turquoise gene module, 20 hub genes were identified positively correlated with CRC, including PAICS, ATR, AASDHPPT, DDX18, NUP107, TOMM6, GTPBP4, RAN, GPN3, SYNCRIP, CPSF3, PTRH2, SSRP1, BZW2, NEMP1, PTPMT1, CCT6A, HEATR1, TRIM27 and MRPL17 (Figure 8). The gene discussed is TOMM6; the disease is colorectal carcinoma.