In Parkinson disease (PD), store depletion and subsequent activation of TRPC1 via STIM1 inhibits the frequency and amplitude of the rhythmic activity in dopaminergic neurons and protects dopaminergic neurons from death, application of PD‐mimicking neurotoxins induces downregulation of TRPC1, overexpression of TRPC1 protects cells against neurotoxin‐mediated cytotoxicity (Sun et al., 2017, 2018). This evidence concerns the gene STIM1 and Parkinson disease.