Among the dozens of putative transcription factors from website predicting, we found that C/EBPβ (CCAAT/enhancer binding protein β) maybe a well‐conserved candidate since C/EBPβ is an aging‐related transcription factor indicated in the GenAge Database, abundantly expressed in the brain and can be activated by AD‐risk factors (Chai et al., 2017). The gene discussed is CEBPB; the disease is Alzheimer disease.