SQSTM1 and age-related macular degeneration: In our previous study, we reported a significant increase in LC3 puncta and p62/SQSTM1 aggregates in RPE cells derived from high risk (homozygous for the Y402H‐CFH polymorphism) and affected AMD patients compared to those derived from low‐risk (homozygous for the wild type CFH) nonaffected subjects, which suggests autophagosome accumulation.21