The pronounced effect of triptorelin (and other GnRH analogs) on the course of endometriosis may be attributed to its capacity to suppress estrogen synthesis, as well as to its ability to inhibit endometrioid foci growth by decreasing the synthesis of anti‐inflammatory cytokines and stimulating apoptosis of ectopic endometrioid cells.10 The gene discussed is GNRH1; the disease is endometriosis.