The role of RANK rs1805034 polymorphism has been analyzed in regard to RA (Mohamed et al. 2016; Yang et al. 2019), cancer (Yin et al. 2014; Zhang et al. 2015), hip osteoporotic fractures (Zhang et al. 2011), knee osteoarthritis (Wang et al. 2019), age at menarche (Duan et al. 2015; Pan et al. 2012) and in Paget’s disease (Chung et al. 2010). The gene discussed is TNFRSF11A; the disease is osteoarthritis, knee.