The following datasets were selected for our analyses: Watanabe17, that investigated gene expression in 53 samples of non-neoplastic rectal mucosa and 67 samples of CRC; Galamb18, that investigated gene expression in 6 microdissected samples from CRC and 6 microdissected samples from non-neoplastic tissues; Carmical19, that investigated gene expression in colorectal CD133+ cancer cells and in cancer-associated fibroblasts (CAFs). Here, PROM1 is linked to cancer.