TGFB1 and chronic rhinosinusitis with nasal polyps: It has been reported that TGF-β from regulatory T cells (Tregs) is related to Tregs production and inhibition function of CD4T cells [93].The decrease of TGF-β 1 expression and TGF-β receptor 2 in CRSwNP results in the absence of Tregs in CRSwNP.