The dysregulation of GBP2, EIF4E, PRR15, ANXA2, PRSS12, HNRNPA3, PFDN2, RGS10, GNG11, and TMSB4X were found in the samples of colon cancer, suggesting that these genes are related to progression of colon cancer. The gene discussed is EIF4E; the disease is malignant colon neoplasm.