The boxplots demonstrating the correlations between the tumor treatment and the hub genes were shown in Figure 3E. Except for Cox17, Pck2, Psmc6, Sms, Ckmt1, Gtf2b and 1110005a03rik, the expression status of hub genes in the red module were negatively correlated with PHY906 treatment. Here, COX17 is linked to neoplasm.