Thus, we speculated that PHY906-CPT11 exerts therapeutic role in colon cancer by regulating the expression of GBP2, EIF4E, PRR15, ANXA2, HNRNPA3, NCF1, C3AR1, PFDN2, RGS10, GNG11, and TMSB4X. This evidence concerns the gene PRR15 and colonic neoplasm.