The dysregulation of GBP2, EIF4E, PRR15, ANXA2, PRSS12, HNRNPA3, PFDN2, RGS10, GNG11, and TMSB4X were found in the samples of colon cancer, suggesting that these genes are related to progression of colon cancer. This evidence concerns the gene PFDN2 and malignant colon neoplasm.