AKT1 and human papilloma virus infection: Among the 7 predicted KEGG pathways, the metabolic pathways represented the largest group, consisting of 898 contigs (5.29%), followed by cancer (290, 1.71%), biosynthesis of secondary metabolites (224, 1.32%), human papillomavirus infection (172, 1.01%) and PI3K-Akt signaling (170, 1.00%) (Fig. 2 and Table S3).