IL2RG and acute myeloid leukemia: In our xenotransplantation model using NOD/Scid/IL2Rγ-KO (NOG) mice, when this fraction was isolated from the mice that developed AML after the 1st transplantation of primary AML cells (Cases #2, #3, #5 and #8) and transplanted into the 2nd mice, all secondary transplanted mice developed AML (Supplementary Fig. 3), indicating that this fraction contains AML initiating cells.