In contrast to the present study, miR-142-3p levels were increased in psoriatic patients and decreased with etanercept treatment in the study by Pivarcsi et al.23Ichıhara et al. have found decreased miR-424 expression in the tissues of psoriasis patients, and observed that decreased miR-424 associated increased MEK1 and cyclin E1 levels may induce keratinocyte proliferation in the epidermis.24 The gene discussed is MAP2K1; the disease is psoriasis.