Low-dimensional flow cytometric analysis also revealed no significant differences in the expression levels of the microglial homeostatic proteins CX3CR1, P2Y12 and GPR56 (ADGRG1) in active MS lesions compared to NAWM (Additional file 1: Supplementary Table 5; Additional file 2: Supplementary Fig. 2c). Here, ADGRG1 is linked to myeloid sarcoma.