Indeed, a subset of Lewy body-like (hyaline) inclusions in the anterior horn cells of 10 out of 20 sporadic ALS patients (albeit with no test on SOD1 mutations) were immunoreactive to anti-SOD1 antibodies, while skein-like inclusions and Bunina bodies were not [62–64]. This evidence concerns the gene SOD1 and amyotrophic lateral sclerosis.