To explore the underlying molecular mechanism of the protective role of SIRT1-modified hUCMSCs on peritoneal fibrosis, we performed qPCR and Western blot to detect the expression and activity of the TGF-β pathway, which has been reported to induce EMT in human endothelial cells recently [26]. The gene discussed is TGFB1; the disease is Peritoneal Fibrosis.