Three processes show similar overlap of GO terms and subnetworks for PD and HGPS, but direct regulation through seed node genes is only observed for one of the diseases (either PD or HGPS) (Tables 3 and S7): “GO:0007076: mitotic chromosome condensation“, “GO:0060024: rhythmic synaptic transmission“ and “GO:0022900: electron transport chain“. The gene discussed is LMNA; the disease is Parkinson disease.