No significant difference in the positive rate of Syn and CgA was observed between pure NEC, > 70% G-HMiNEN, G-HMiNEN, and < 30% G-HMiNEN (Fig. 2b, c), only the positive rate of CD56 was found to be higher in the pure NEC group than that in the < 30% G-HMiNEN group (Fig. 2d). This evidence concerns the gene NCAM1 and neuroendocrine carcinoma.