PNPLA3 and metabolic dysfunction-associated steatotic liver disease: We found that the PNPLA3 rs738409 G/C gene polymorphism was associated NAFLD in children under four genetic models.(For GG + GC vs CC OR = 3.157, 95% CI = 1.446–6.892, P = 0.004; Fig. 2.For G vs C OR = 3.343, 95% CI = 1.524–7.334, P = 0.003;Fig. 3.For GG vs GC + CC OR = 5.692, 95% CI = 1.941–16.689, P = 0.002;Fig. 4.For GG + CC vs GC OR = 2.756, 95% CI = 1.729–4.392, P = 0.000;Fig. 5, respectively),suggesting G allele was a risk factor for NAFLD risk in children.