Taken together, considering the expression pattern of YTHDF1/2 in prostate cancer, bladder cancer and other cancers, and the role of YTHDF1/2 in the carcinogenesis of prostate cancer and bladder cancer, YTHDF1/2 could be a promising biomarker and prognostic indicator in prostate cancer and bladder cancer. This evidence concerns the gene YTHDF1 and urinary bladder carcinoma.