Taken together, considering the expression pattern of METTL3 in prostate cancer, bladder cancer and other cancers, and the role of METTL3 in the carcinogenesis of prostate cancer and bladder cancer, METTL3 could be a promising biomarker and prognostic indicator in prostate cancer and bladder cancer. The gene discussed is METTL3; the disease is prostate carcinoma.