For many autoimmune diseases (such as RA, SLE, psoriasis, autoimmune thyroid disease and Crohn's disease), dysregulation of lncRNAs correlated with the abnormal development of immune cells (e.g., dendritic cells, granulocytic and T cells) and expression of proinflammatory cytokines (including IFN‐γ) [24, 25, 26, 27, 28]. The gene discussed is IFNG; the disease is autoimmune disease.